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- M Fornaro, O Hess, F Benoist, and M Turina.
- Thoraxchir Vask Chir. 1978 Jun 1; 26 (3): 190-3.
AbstractHaemodynamic changes after intracoronary air embolism (0,02 ml/kg air in the left coronary artery) were studied in 16 dogs. The air was introduced in 8 animals during cardiopulmonary bypass and in 8 animals without bypass. In both groups the air embolization caused acute ischemia with myocardial necrosis. Immediately after the injection the anterior wall became akinetic; 24 hours after injection CPK increased to more than 800 U. One half of the animals without cardiopulmonary bypass died during acute ischemia due to refractory arrhythmias; there was no mortality in the group with cardiopulmonary bypass. The left ventricular damage due to air embolization cannot be significantly reduced with cardiopulmonary bypass; the bypass only helps to "tide over" the animal during the period of acute ischemia.
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