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Randomized Controlled Trial Comparative Study Clinical Trial
Maternal and neonatal responses to alfentanil administered before induction of general anaesthesia for caesarean section.
- W L Dann, A Hutchinson, and D P Cartwright.
- Derby City Hospital.
- Br J Anaesth. 1987 Nov 1; 59 (11): 1392-6.
AbstractThe cardiovascular response to tracheal intubation was compared in two groups of patients undergoing elective Caesarean section. Both groups received a standard technique of general anaesthesia. One of the groups received alfentanil 10 micrograms kg-1 1 min before induction of anaesthesia, the other acted as a control group. In the alfentanil group there was a significant modification of the cardiovascular response to intubation as compared with the control group (P less than 0.01). No adverse effect on the neonate was seen. However, a significant increase in the incidence of postoperative nausea occurred in mothers in the alfentanil group (P less than 0.05).
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