• Respiratory care · Jul 2015

    Case Reports

    Diffuse Interstitial Pulmonary Infiltrates in Malignant Melanoma.

    • Jens Bräunlich, Hans-Jürgen Seyfarth, Armin Frille, and Hubert Wirtz.
    • Department of Pulmonary Medicine, University of Leipzig, Leipzig, Germany. highflow@web.de.
    • Respir Care. 2015 Jul 1;60(7):e115-7.

    AbstractOnly a few cases of sarcoidosis-like reaction to a pharmacologic compound have been reported in patients with melanoma in the literature. Long-term treatment with interferon alpha may be assumed. We report a case of a 25-y-old man who presented to our department with diffuse interstitial pulmonary infiltrates and slightly enlarged mediastinal lymph nodes as determined by computed tomography. He had a history of malignant melanoma with 18 months of interferon alpha-2 therapy. Histological analysis of a transbronchial biopsy revealed sarcoidosis-like reactions.Copyright © 2015 by Daedalus Enterprises.

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