• Br J Anaesth · Apr 1986

    Randomized Controlled Trial Comparative Study Clinical Trial

    Comparison of the incidence and nature of cardiac arrhythmias occurring during isoflurane or halothane anaesthesia. Studies during dental surgery.

    • M R Rodrigo, T M Moles, and P K Lee.
    • Br J Anaesth. 1986 Apr 1; 58 (4): 394-400.

    AbstractSeventy-six Chinese patients aged between 15 and 30 yr, undergoing 3rd molar extraction, were randomly allocated to two groups. One group received halothane and the other isoflurane. The incidence of arrhythmia during surgery under anaesthesia with isoflurane was significantly less than with halothane. Sinus tachycardia was a significant feature under anaesthesia with isoflurane. Under anaesthesia with halothane, the arrhythmias occurring most frequently during surgery were ventricular ectopics, the commonest being ventricular bigeminy. The frequency and nature of arrhythmias during surgery on right and left sides were similar. In three patients a slight decrease in arterial pressure was recorded in association with the arrhythmia, but on stopping the stimulus, both rhythm and arterial pressure returned to normal. The incidence of arrhythmia with halothane in the Chinese population in this study was significantly higher than that reported previously in non-Chinese patients.

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