• J. Am. Vet. Med. Assoc. · Oct 2001

    Randomized Controlled Trial Clinical Trial

    Prolonged anesthesia with desflurane and fentanyl in dogs during conventional and laparoscopic surgery.

    • M F Martín, J R Lima, L J Ezquerra, M S Carrasco, and J Usón-Gargallo.
    • Minimally Invasive Surgery Centre, Cáceres, Spain.
    • J. Am. Vet. Med. Assoc. 2001 Oct 1; 219 (7): 941-5.

    ObjectiveTo determine the effects of prolonged anesthesia with desflurane in dogs undergoing laparotomy or abdominal laparoscopy.DesignRandomized prospective study.Animals20 adult mixed-breed dogs.ProcedureDogs were randomly assigned to 1 of 2 groups with 10 dogs/group. Anesthesia was induced with propofol and maintained with desflurane and fentanyl, and pyloroplasty was performed. In 10 dogs, a ventral midline laparotomy was performed; in the other 10, abdominal laparoscopy was performed. Dogs were monitored for cardiovascular and respiratory responses (ECG, oxygen saturation [SpO2], arterial blood pressure, rectal temperature, end-tidal partial pressure of carbon dioxide [PETCO2], and expired desflurane concentration). Recovery times were recorded.ResultsMean +/- SD duration of anesthesia was 201 +/- 25 minutes for dogs undergoing laparotomy and 287 +/- 15 minutes for dogs undergoing laparoscopy. Anesthesia was accompanied by hypotension that was less severe in dogs undergoing laparoscopy. Heart rate did not vary significantly during anesthesia. The SpO2 was > 97% in all dogs at all times, and PETCO2 remained within reference limits. Recovery times for dogs that underwent laparotomy were not significantly different from those for dogs that underwent laparoscopy. Mean +/- SD time to standing was 13.6 +/- 2.4 minutes for dogs that underwent laparotomy and 12.5 +/- 2.9 minutes for dogs that underwent laparoscopy.Conclusions And Clinical RelevanceResults suggest that induction of anesthesia with propofol and maintenance with desflurane and fentanyl is safe in dogs undergoing abdominal surgery.

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