• Blood · Mar 2014

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    Two faces of ET: CALR and JAK2.

    • Mark P Chao and Jason Gotlib.
    • INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE;
    • Blood. 2014 Mar 6; 123 (10): 1438-40.

    AbstractIn this issue of Blood, Rumi et al and Rotunno et al demonstrate that essential thrombocythemia (ET) patients with calreticulin mutations exhibit lower leukocyte and hemoglobin values, higher platelet counts, and a lower thrombosis risk vs JAK2-mutated ET. Calreticulin-mutated ET appears to be a distinct entity with a more indolent course.

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