• Mariana Àlvares de Abreu e Silva, Fernanda Gonçalves Salum, Maria Antonia Figueiredo, and Karen Cherubini.
• Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
• Mycoses. 2013 May 1; 56 (3): 189-99.

AbstractParacoccidioidomycosis is a deep mycosis endemic to Latin America, with considerable morbidity and mortality. It is caused by the dimorphic fungus Paracoccidioides brasiliensis, which affects, among other organs in the human body, the oral cavity. Fungus virulence and immunocompetence of the host determine the establishment of infection or active disease, whose severity and clinical behaviour depend mostly on the cellular immune response of the host. Often, oral lesions constitute the first sign and site of confirmation of diagnosis, which in most cases is delayed. The success of the treatment depends on early and correct diagnosis, as well as on the patient's adherence to the drug therapy.© 2012 Blackwell Verlag GmbH.

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