• American family physician · Dec 1989

    Review Case Reports

    Acute arsenic intoxication.

    • J P Campbell and J A Alvarez.
    • University of Oklahoma Health Sciences Center, Oklahoma City.
    • Am Fam Physician. 1989 Dec 1; 40 (6): 93-7.

    AbstractThe diagnosis of acute arsenic poisoning should be considered in any patient presenting with severe gastrointestinal complaints. Signs and symptoms include nausea, vomiting, colicky abdominal pain and profuse, watery diarrhea. Hypotension, fluid and electrolyte disturbances, mental status changes, electrocardiographic abnormalities, respiratory failure and death can result. Quantitative measurement of 24-hour urinary arsenic excretion is the only reliable laboratory test to confirm arsenic poisoning. Treatment includes gastric emesis or lavage, chelation therapy, electrolyte and fluid replacement, and cardiorespiratory support.

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