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J Hyg Epidemiol Microbiol Immunol · Jan 1990
Historical ArticleSmallpox diagnosed 400 years later: results of skin lesions examination of 16th century Italian mummy.
- S S Marennikova, E M Shelukhina, O A Zhukova, N N Yanova, and V N Loparev.
- Research Institute for Viral Preparations, Moscow, USSR.
- J Hyg Epidemiol Microbiol Immunol. 1990 Jan 1; 34 (2): 227-31.
AbstractResults are presented on virological examination conducted on WHO request of a Naples infant mummy with smallpox-like lesions. Electron microscopy of lesions confirmed the findings of Italian researchers: well-preserved virus-like structures, whose size and morphology were identical to those of orthopoxviruses have been revealed. It was shown that the virus in mummy skin had lost its viability. Viral antigenic activity could not be detected in EIA or RPHA, nor was determined its DNA in the test of DNA molecular hybridization.
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