• Resuscitation · Mar 1984

    Review

    Place of vasoactive agents in the treatment of acute circulatory failure.

    • J L Vincent.
    • Resuscitation. 1984 Mar 1; 11 (3-4): 175-82.

    AbstractIncrease in total cardiac output can improve oxygen delivery to the cells. Although inotropic drugs increase primarily myocardial contractility, they can adversely affect cardiac preload and afterload. Moreover, they can dangerously increase myocardial oxygen requirements. The combined use of vasodilating agents, with fluid challenge represents a challenging but more efficient treatment of acute circulatory failure.

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