• Anup Thakur, Satish Saluja, Manoj Modi, Neelam Kler, Pankaj Garg, Arun Soni, Avneet Kaur, and Sanjeev Chetri.
• Department of Neonatology, Institute of Child health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi 110060, India.
• Resuscitation. 2015 May 1;90:21-4.

ObjectiveTo compare the duration of positive pressure ventilation (PPV) during delivery room resuscitation in neonates resuscitated with self-inflating bag (SIB) and T-piece resuscitator (TPR).DesignRandomized control trial.SettingDelivery room and neonatal intensive care unit of a tertiary care center in northern India.PatientsConsecutively born neonates more than 26 weeks of gestation requiring PPV at birth.InterventionEligible neonates were randomized to two groups, SIB and TPR.Outcome MeasuresDuration of PPV, intubation rates in delivery room, incidence of respiratory distress, need for mechanical ventilation during first 48h and its duration, need for surfactant replacement therapy and mortality during NICU stay.ResultsFifty neonates received PPV with a SIB and 40 received PPV with a TPR. The mean (SD) birth weight and gestational age of neonates in SIB and TPR groups were 2264 (872) and 2065 (814)g; 35.1 (3.6) and 34.3 (3.7) weeks, respectively. The median (IQR) duration of PPV in delivery room was significantly less in TPR group as compared to SIB; 30 (30-60)s vs. 60 (30-90)s, respectively; (p<0.001). A higher proportion of neonates required delivery room intubation in SIB group as compared to TPR group (34% vs. 15%, p=0.04). In the TPR group, a higher proportion of neonates could be resuscitated with room air only (72.5% vs. 38%, p=0.001). Other outcomes were comparable in the two groups. Similar findings were observed in neonates <34 weeks, except that fewer neonates resuscitated with TPR required invasive ventilation (31.6% vs. 77.8%, p=0.008).ConclusionUse of TPR during delivery room resuscitation resulted in shorter duration of PPV and lesser rates of intubation as compared to SIB. More infants in this group could be resuscitated with room air only (CTRI/2010/091/002946).Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

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