• Clin Electroencephalogr · Jul 1994

    Case Reports

    Propofol, seizures and generalized paroxysmal fast activity in the EEG.

    • W J Nowack and R Jordan.
    • Department of Neurology, University of South Alabama, Mobile 36617.
    • Clin Electroencephalogr. 1994 Jul 1; 25 (3): 110-4.

    AbstractPropofol is a relatively new anesthetic agent used in outpatient surgery. Some investigators use it in the treatment of status epilepticus and in epilepsy surgery and have concluded that propofol has an anticonvulsant effect. Cases of seizure-like behaviors, myoclonus and opisthotonus following propofol anesthesia have been reported. Although rare, official warnings about this association have been issued. Different EEG abnormalities, and no abnormality, have been associated with propofol. We report a case of a healthy man who developed nonconvulsive seizures and generalized paroxysmal fast activity in his EEG following use of propofol for anesthesia.

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