• Ann R Coll Surg Engl · Sep 1984

    Randomized Controlled Trial Comparative Study Clinical Trial

    Evaluation of anti-emetics in association with intrathecal diamorphine.

    • D W Barron.
    • Ann R Coll Surg Engl. 1984 Sep 1; 66 (5): 359-60.

    AbstractIntrathecal diamorphine is associated with a high incidence of emetic symptoms. Six anti-emetic drugs representing various chemical groups were given in random order to patients undergoing total hip replacement and who had received intrathecal diamorphine 0.5-1.0 mg. The phenothiazines, perphenazine and prochlorperazine, were more effective than the others. It is suggested that this might be a useful model for the evaluation of new anti-emetics.

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