• Carl O Eriksson, Timothy M Uyeki, Michael D Christian, Mary A King, Dana A V Braner, Robert K Kanter, and Niranjan Kissoon.
• 1Division of Pediatric Critical Care, Department of Pediatrics, Oregon Health & Science University, Portland, OR. 2Influenza Division, National Center for Immunization and Respiratory Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA. 3Department of Critical Care, Mount Sinai Hospital, Toronto, ON, Canada. 4Pediatric Critical Care Medicine, Seattle Children's Hospital and Harborview Medical Center, Seattle, WA. 5Pediatric Critical Care Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA. 6National Center for Disaster Preparedness, Columbia University, New York, NY. 7Departments of Pediatrics and Emergency Medicine, British Columbia's Children's Hospital, Vancouver, BC, Canada.
• Pediatr Crit Care Me. 2015 Feb 1;16(2):97-103.

ObjectivesTo provide clinicians with practical considerations for care of children with Ebola virus disease in resource-rich settings.Data SourcesReview of the published medical literature, World Health Organization and government documents, and expert opinion.Data SynthesisThere are limited data regarding Ebola virus disease in children; however, reported case-fatality proportions in children are high. Ebola virus may affect immune regulation and endothelial function differently in children than adults. Considerations for care of children with Ebola virus disease are presented.ConclusionsEbola virus disease is a severe multisystem disease with high mortality in children and adults. Hospitals and clinicians must prepare to provide care for patients with Ebola virus disease before such patients present for care, with particular attention to rigorous infection control to limit secondary cases. Although there is no proven specific treatment for Ebola virus disease, meticulous supportive care offers patients the best chance of survival.

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