• Anneliese Nusmeier, Corrado Cecchetti, Martin Blohm, Rick Lehman, Johannes van der Hoeven, and Joris Lemson.
• 1Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands. 2Emergency Department and Pediatric Intensive Care Unit, Pediatric Hospital "Bambino Gesù", IRCCS, Rome, Italy. 3Sektion Neonatologie/Pädiatrische Intensivmedizin, Universitätskinderklinik Hamburg-Eppendorfs, Hamburg, Germany. 4Pediatric Critical Care Medicine, University of California, Santa Barbara, CA.
• Pediatr Crit Care Me. 2015 Feb 1;16(2):e28-33.

ObjectivesTo define near-normal values of extravascular lung water indexed to body weight in children.DesignProspective multicenter observational study.SettingMedical/surgical PICUs of 5 multinational hospitals.PatientsFifty-eight children with a median age of 4 years (range 1 month to 17 year) with heterogeneous PICU admission diagnoses were included. Extravascular lung water measurements from these children were collected after resolution of their illness. Obtained values were indexed to actual body weight and height and subsequently related to age.InterventionsNone.Measurements And Main ResultsExtravascular lung water indexed to body weight correlated with age (r2 = 0.7) and could be categorized in three-age groups consisting of significantly different median extravascular lung water indexed to body weight values (5th-95th percentile): less than 1 year, 9-29 mL/kg; 1-5 years, 7-25 mL/kg; and 5-17 years, 5-13 mL/kg. Extravascular lung water indexed to height did not correlate to age and resulted in an age-independent near-normal value of less than 315 mL/m.ConclusionsYounger children have higher values of extravascular lung water indexed to actual body weight. Age categorized near-normal values of extravascular lung water indexed to body weight are presented for possible clinical use. Furthermore, we suggest to index extravascular lung water to height, which seems to be age independent.

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