• Expert Rev Pharmacoecon Outcomes Res · Dec 2011

    Review

    The impact of reference-pricing systems in Europe: a literature review and case studies.

    • Pieter Dylst, Arnold Vulto, and Steven Simoens.
    • Research Centre for Pharmaceutical Care & Pharmaco-economics, KU Leuven, Belgium, Herestraat 49, O&N 2, PO Box 521, 3000 Leuven, Belgium. pieter.dylst@pharm.kuleuven.be
    • Expert Rev Pharmacoecon Outcomes Res. 2011 Dec 1; 11 (6): 729-37.

    AbstractAs healthcare budgets are continuously rising in Europe, governments implement a wide variety of policies to control them. Reference pricing is a popular tool for governments to contain pharmaceutical expenditures, as 22 European countries have implemented this system. This article evaluates the impact of reference-pricing systems on drug use, drug prices, drug expenditure and health outcomes. In addition, two case studies, one for statins and one for proton-pump inhibitors, were carried out. Reference pricing drives down prices of drugs subject to the system and the use of these drugs has increased. Reference pricing creates short-term savings but the long-term growth of drug expenditure has not been reduced by reference pricing. Health outcomes of patients were not negatively affected by the system.

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