• C J Cabilan, Robert Eley, James A Hughes, and Michael Sinnott.
• Department of Emergency Medicine, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
• J Adv Nurs. 2016 Feb 1; 72 (2): 396-408.

AimsTo assess the medication knowledge of emergency department nurses and determine the factors affecting their nurse-initiated medication practices.BackgroundNurse-initiated medications is a vital practice for all nurses in emergency departments which improves pain assessment, provides safe pain management and reduces time-to-analgesia and other meaningful treatments.DesignMixed methods. Between September 2014-January 2015, data were collected by questionnaire assessing medication knowledge and face-to-face interviews determining factors affecting practice.ResultsNurse-initiated medications frequency of the Registered Nurses ranged from 0-36 times per week dependent on employed hours and emergency department area worked. Medication knowledge was consistent among nurses, but there was an overall deficit in nurses' knowledge of mechanism of action. Four major themes were identified from the 24 interviews: patient-centred care, caution and safety as principles of practice; continuing support and education; improvement of practice over time. All nurses regard the practice positively and to be extremely beneficial to patients. Although apprehensive at the start of their nurse-initiated medications practice, confidence improved with exposure and experience. Nurses sought additional information from colleagues and the available evidence-based resources.ConclusionMedication knowledge is not the sole determinant of nurse-initiated medications practice. The practice is motivated by multiple factors such as patients' needs, safety and nurses' confidence.© 2015 John Wiley & Sons Ltd.

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