• Annals of hematology · May 2003

    Case Reports

    Leukemoid reaction response to chemotherapy and radiotherapy in a patient with cervical carcinoma.

    • H S Nimieri, S N Makoni, F H Madziwa, and D S Nemiary.
    • Department of Internal Medicine, Mercy Fitzgerald Hospital, 1500 Lansdowne Ave., Darby, PA 19018, USA.
    • Ann. Hematol. 2003 May 1; 82 (5): 316-7.

    AbstractA white blood cell count more than 50 x 10(9)/l associated with a cause outside the bone marrow is termed a leukemoid reaction. Although it simulates leukemia, most of its causes are benign. Malignancy as a cause of a leukemoid reaction is still a medical dilemma. It is thought to be attributed to granulocyte colony-stimulating factor (G-CSF) secreted by the tumor cells. To our knowledge this is the first time a leukemoid reaction has been reported in association with cervical cancer. We even managed to monitor the leukemoid reaction response to chemotherapy and radiotherapy.

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