• Ann. Thorac. Surg. · Jan 2014

    Case Reports

    Diffuse pulmonary neuroendocrine cell hyperplasia involving the chest wall.

    • Adnan M Al-Ayoubi, Jonathan S Ralston, S Russ Richardson, and Chadrick E Denlinger.
    • Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, South Carolina.
    • Ann. Thorac. Surg. 2014 Jan 1; 97 (1): 333-5.

    AbstractDiffuse pulmonary neuroendocrine cell hyperplasia (DIPNECH) is characterized by a diffuse hypertrophy of neuroendocrine cells along the distal bronchioles. This condition is characterized by obstructive lung physiology and the development of small carcinoid tumors. We present a case of DIPNECH in a patient undergoing surgery for a primary lung adenocarcinoma. Interestingly, the chest wall also demonstrated involvement of DIPNECH indicated by the presence of small carcinoid tumors. The absence of any lung carcinoid tumor greater than 5 mm and the absence of lymph node metastases render the chest wall involvement unlikely to represent metastatic disease.Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

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