• Medicina intensiva · Mar 2015

    Nebulized antibiotics. An adequate option for treating ventilator-associated respiratory infection?

    • A Rodríguez and F Barcenilla.
    • Servicio de Medicina Intensiva, Hospital Universitario de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Tarragona, España; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), España. Electronic address: ahr1161@yahoo.es.
    • Med Intensiva. 2015 Mar 1; 39 (2): 97-100.

    AbstractVentilator-associated tracheobronchitis (VAT) is a frequent complication in critical patients. The 90% of those who develop it receive broad-spectrum antibiotic (ATB) treatment, without any strong evidence of its favorable impact. The use of nebulized ATB could be a valid treatment option, to reduce the use of systemic ATB and the pressure of selection on the local flora. Several studies suggest that an adequate nebulization technique can ensure high levels of ATB even in areas of lung consolidation, and to obtain clinical and microbiological cure. New studies are needed to properly assess the impact of treatment with nebulized ATB on the emergence of resistance.Copyright © 2014 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

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