• Anant Mehrotra, Pradeep Sharma, Kuntal Kanti Das, Kamlesh Singh Bhaisora, Jayesh Sardhara, Shruti Gupta, Satyadeo Pandey, Awadhesh Kumar Jaiswal, Rabi Narayan Sahu, Arun Kumar Srivastava, and Sanjay Behari.
• Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. Electronic address: dranantmehrotra@gmail.com.
• World Neurosurg. 2016 Aug 1; 92: 126-132.

BackgroundTo highlight the management nuances in addressing mirror aneurysms (MirAns) in a subset of multiple aneurysms.MethodsA retrospective study was carried out and all multiple intracranial aneurysms (n = 70) over 9 years were identified. Exclusion criteria were associated arteriovenous malformations, moyamoya disease, and either traumatic or mycotic aneurysms or those managed by endovascular approach alone. Patients were grouped as MirAn and nonmirror aneurysms (nMirAns). Outcome was assessed by Glasgow Outcome Score at 1 month. The Pearson χ(2) test or Fisher exact test were used to establish association.ResultsMirAns (n = 17) accounted for 2.1% of all intracranial aneurysms and 24.3% of multiple aneurysms. Female predilection was eminent in the MirAn group (3.25:1) compared with the nMirAn group (2.5:1). The middle cerebral artery (n = 6) followed by the internal carotid artery-posterior communicating artery (n = 5) were the most common sites of the MirAns. There was no significant difference between the 2 groups for hypertension or age (MirAn, 52 years [± 11.231]; hypertension, 52.9%; nMirAn, 48.58 years [± 12.97]; hypertension, 54.7%). There was a definite trend towards less intraoperative rupture (MirAn, 4/17; nMirAn, 27/53; P = 0.048), decreased intraoperative vasospasm (MirAn, 1; nMirAn, 11) in the MirAn group. Development of infarct was significantly less in the MirAn group (P = 0.027) with a better outcome (13 in MirAn and 26 in nMirAn had good outcome; P = 0.048).ConclusionsMirAns are not significantly associated with risk factors such as age, hypertension, and diabetes. Intraoperative rupture, vasospasm, and infarct are less common, with a tendency towards better neurologic outcome compared with nMirAns.Copyright © 2016 Elsevier Inc. All rights reserved.

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