• Ana Laura Colle Kauling, Maria Cristina Simões de Almeida, Giovani de Figueiredo Locks, and Guilherme Muriano Brunharo.
• Universidade de São Paulo, SP, Brazil. analaurakauling@gmail.com
• Rev Bras Anestesiol. 2011 Nov 1; 61 (6): 748-63.

Background And ObjectivesMyasthenia gravis (MG) is an autoimmune neurologic disease that affects the postsynaptic portion of the neuromuscular junction. It represents a challenge for anesthesiologists due to the diversity of disease manifestations and possibility of postoperative respiratory complications. The objective of this study was to demonstrate the importance of adequate monitoring of the neuromuscular blockade (NMB) due to the multiple presentations of MG.ContentsIn this paper we report two cases of patients with MG. The first patient presented with the classical sensitivity to the neuromuscular blocker (NMB) and the second had a similar response to that of a normal patient. The literature review will be restricted to disease characteristics, while the description of its pathophysiology will focus on its reactions to NMB.ConclusionsWe suggest that, due to the multiple presentation and treatment of MG, neuromuscular transmission monitors are fundamental when using NMB.Copyright © 2011 Elsevier Editora Ltda. All rights reserved.

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