Dabigatran-related intracerebral hemorrhage resulting in

J Stroke Cerebrovasc Dis · Feb 2014

Case Reports

Dabigatran-related intracerebral hemorrhage resulting in hematoma expansion.

Warfarin-related intracerebral hemorrhage carries a particularly high risk of neurologic deterioration and death because of a high rate of hematoma expansion of about 50%. Novel oral anticoagulants (NOACs)--apixaban, dabigatran, and rivaroxaban--have a significantly smaller risk of intracerebral hemorrhage (ICH). ⋯ Second, there is no specific antidote for neither of the NOACs. We present a case that suggests that hematoma expansion may occur after NOAC-related ICH.

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- Claus Z Simonsen, Thorsten Steiner, Anna Tietze, and Dorte Damgaard.
- Department of Neurology, Aarhus University Hospital, Aarhus, Denmark. Electronic address: clasim@rm.dk.
- J Stroke Cerebrovasc Dis. 2014 Feb 1; 23 (2): e133-4.
AbstractWarfarin-related intracerebral hemorrhage carries a particularly high risk of neurologic deterioration and death because of a high rate of hematoma expansion of about 50%. Novel oral anticoagulants (NOACs)--apixaban, dabigatran, and rivaroxaban--have a significantly smaller risk of intracerebral hemorrhage (ICH). However, two facts make this situation complicated: First, the risk of hematoma expansion is unknown for NOACs. Second, there is no specific antidote for neither of the NOACs. We present a case that suggests that hematoma expansion may occur after NOAC-related ICH.Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.

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Dabigatran-related intracerebral hemorrhage resulting in hematoma expansion.

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