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J. Clin. Microbiol. · Nov 2010
Single-nucleotide polymorphism in the fadD28 gene as a genetic marker for East Asia Lineage Mycobacterium tuberculosis.
- Pei-Chun Chuang, Huang-Yau Chen, and Ruwen Jou.
- Reference Laboratory of Mycobacteriology, Research and Diagnostic Center, Centers for Disease Control, 161 Kun-Yang Street, Nan-Kang, Taipei 115, Taiwan, Republic of China.
- J. Clin. Microbiol. 2010 Nov 1; 48 (11): 4245-7.
AbstractMycobacterium tuberculosis isolates with a region of difference 105 (RD105) deletion, mainly Beijing family spoligotypes, were phylogenetically grouped into the East Asia lineage. We identified a single nucleotide polymorphism in codon 507, ATC to ATT, of the fadD28 gene as a robust marker and developed a rapid assay for East Asia lineage M. tuberculosis.
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