• Gastrointest. Endosc. Clin. N. Am. · Jan 2005

    Review

    Endoscopic ultrasound-guided fine-needle injection.

    • Jason B Klapman and Kenneth J Chang.
    • Division of Gastroenterology, University of California Irvine Medical Center, 101 The City Drive, Building 22C, Route 99, Orange, California 92868, USA.
    • Gastrointest. Endosc. Clin. N. Am. 2005 Jan 1; 15 (1): 169-77, x.

    AbstractWith the development of linear array echoendoscopes and the ability to perform endoscopic ultrasound (EUS)-guided fine-needle aspiration, the delivery of therapeutic agents with fine-needle injection (FNI) emerged. EUS-guided FNI is an attractive delivery system because of its minimal invasiveness and low complication rate. This approach is effective in performing celiac plexus neurolysis for pain relief in patients with pancreatic cancer. The most exciting area of interest involves the delivery of antitumor agents in patients with locally advanced cancer, such as cancer of the pancreas or esophagus. The involvement of EUS-guided FNI in tumor therapy adds a host of potential new applications that continue to swing the pendulum of EUS from a diagnostic to a therapeutic modality.

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