• Br J Hosp Med · Feb 1997

    Review

    Opioid analgesics.

    • A R Rushton and J R Sneyd.
    • Department of Anaesthesia, Derriford Hospital, Plymouth.
    • Br J Hosp Med. 1997 Feb 5; 57 (3): 105-6.

    AbstractThis article discusses recent developments in opioid pharmacology. Selective activity at different opioid receptors promises, but has not yet provided, a strong analgesic without opioid side-effects. The startling pharmacokinetic profile of the new esterase-metabolized intravenous opioid, remifentanil, is reflected in the rapid onset of effect and short, predictable recovery, independent of duration of infusion.

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