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Randomized Controlled Trial Clinical Trial
Modulation of thermal pain-related brain activity with virtual reality: evidence from fMRI.
- Hunter G Hoffman, Todd L Richards, Barbara Coda, Aric R Bills, David Blough, Anne L Richards, and Sam R Sharar.
- Human Interface Technology Lab, and Department of Radiology, Box 352142, University of Washington, 1959 NE Pacific, Seattle, WA 98195, USA. hunter@hitL.washington.edu
- Neuroreport. 2004 Jun 7; 15 (8): 1245-8.
AbstractThis study investigated the neural correlates of virtual reality analgesia. Virtual reality significantly reduced subjective pain ratings (i.e. analgesia). Using fMRI, pain-related brain activity was measured for each participant during conditions of no virtual reality and during virtual reality (order randomized). As predicted, virtual reality significantly reduced pain-related brain activity in all five regions of interest; the anterior cingulate cortex, primary and secondary somatosensory cortex, insula, and thalamus (p<0.002, corrected). Results showed direct modulation of human brain pain responses by virtual reality distraction.Copyright 2004 Lippincott Williams and Wilkins
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