• Semin Respir Infect · Dec 2001

    Comparative Study Clinical Trial

    Rapid diagnostic evaluation of bronchial washings in patients with suspected coccidioidomycosis.

    • G A Sarosi, J P Lawrence, D K Smith, A Thomas, D W Hobohm, and P C Kelley.
    • Department of Medicine, Maricopa Medical Center, Phoenix, AZ, USA.
    • Semin Respir Infect. 2001 Dec 1; 16 (4): 238-41.

    AbstractCoccidioidomycosis is a regionally common fungal infection, primarily affecting the lung. While in the majority of cases the tempo of the disease allows for a more leisurely diagnostic plan, including multiple serologic tests and culture of respiratory secretions, occasionally, patients will present with rapidly progressive, life-threatening pulmonary illness, in whom there is an urgent need for rapid diagnosis. Evaluation of respiratory secretions including expectorated sputum as well as bronchial washings are frequently available or obtained for diagnosing pulmonary infiltrates. We compared the sensitivity of the Papanicolaou stain with 10% potassium hydroxide digestion (10% KOH) and with calcofluor white (cw). The Papanicolaou test performed the best and should be used in the evaluation of suspected patients with coccidioidomycosis.Copyright 2001 by W.B. Saunders Company

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