• Br J Anaesth · Mar 1980

    Observations on extradural morphine analgesia in various pain conditions.

    • F Magora, D Olshwang, D Eimerl, J Shorr, R Katzenelson, S Cotev, and J T Davidson.
    • Br J Anaesth. 1980 Mar 1; 52 (3): 247-52.

    AbstractWe report the extradural administration of low-dose morphine in 10 ml of 10% dextrose (2-3 mg) to 98 adult patients with various types of acute and chronic pain. Extradural morphine injections were given either via a Tuohy needle (single or repeat injection) or via an extradural catheter. Pain relief was evaluated by subjective scoring and by the subsequent need for systemic analgesics. In 56% of patients, pain relief was considered good or excellent, in 24% it was fair, and in 20%, poor. The best results were after surgery and trauma and in patients with advanced peripheral vascular disease. The analgesia of each dose of extradural morphine lasted for 8 h (mean range 4-36 h). There was no motor, sensory or sympathetic blockade and no respiratory or haemodynamic complications. Dizziness and vomiting occurred in two patients, and urinary retention for about 12 h in three.

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