• Der Radiologe · Nov 2000

    Review Comparative Study

    [Isolated vasculitis of the central nervous system].

    • F Block and W Reith.
    • Neurologische Klinik, RWTH Aachen, Pauwelsstr. 30, 52057 Aachen.
    • Radiologe. 2000 Nov 1; 40 (11): 1090-7.

    AbstractVasculitis is a rare cause for disease of the CNS. The isolated vasculitis of the CNS is restricted to the CNS whereas other forms of vasculitis affect various organs including the CNS. Headache, encephalopathy, focal deficits and epileptic seizures are the major symptoms suggestive for vasculitis. One major criterion of the isolated vasculitis of the CNS is the lack of evidence for other vasculitis forms or for pathology of other organs. Angiography displays multifocal segmental stenosis of intracranial vessels. MRI demonstrates multiple lesions which in part show enhancement after gadolinium. A definite diagnosis can only be made on the grounds of biopsy from leptomeninges and parenchyma. Therapy consists of corticosteroids and cyclophosphamid.

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