• M J Reiss, D A Labowitz, S Forman, and G P Wormser.
• Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla, NY, USA.
• Arch Intern Med. 2001 Feb 12; 161 (3): 461-5.

BackgroundColor blindness is a common hereditary X-linked disorder.ObjectiveTo investigate whether color blindness affects the ability to detect the presence of blood in body fluids.MethodsTen color-blind subjects and 20 sex- and age-matched control subjects were shown 94 photographs of stool, urine, or sputum. Frank blood was present in 57 (61%) of the photographs. Surveys were done to determine if board-certified internists had ever considered whether color blindness would affect detection of blood and whether an inquiry on color blindness was included in their standard medical interview.ResultsColor-blind subjects were significantly less able to identify correctly whether pictures of body fluids showed blood compared with non-color-blind controls (P =.001); the lowest rate of correct identifications occurred with pictures of stool (median of 26 [70%] of 37 for color-blind subjects vs 36.5 [99%] of 37 for controls; P<.001). The more severely color-blind subjects were significantly less accurate than those with less severe color deficiency (P =.009). Only 2 (10%) of the 21 physicians had ever considered the possibility that color blindness might affect the ability of patients to detect blood, and none routinely asked their patients about color blindness.ConclusionsColor blindness impairs recognition of blood in body fluids. Color-blind individuals and their health care providers need to be made aware of this limitation.

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