-
Am J Alzheimers Dis Other Demen · Feb 2009
ReviewNeural stem cells and Alzheimer's disease: challenges and hope.
- Zhongling Feng Bio Group, Nitto Denko Technical Corporation, Oceanside, California 92058, USA. Zhongling_feng@gg.nitto.co.jp, Gang Zhao, and Lei Yu.
- Bio Group, Nitto Denko Technical Corporation, Oceanside, California 92058, USA. Zhongling_feng@gg.nitto.co.jp
- Am J Alzheimers Dis Other Demen. 2009 Feb 1; 24 (1): 52-7.
AbstractAlzheimer's disease is characterized by degeneration and dysfunction of synapses and neurons in brain regions critical for learning and memory functions. The endogenous generation of new neurons in certain regions of the mature brain, derived from primitive cells termed neural stem cells, has raised hope that neural stem cells may be recruited for structural brain repair. Stem cell therapy has been suggested as a possible strategy for replacing damaged circuitry and restoring learning and memory abilities in patients with Alzheimer's disease. In this review, we outline the promising investigations that are raising hope, and understanding the challenges behind translating underlying stem cell biology into novel clinical therapeutic potential in Alzheimer's disease.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..