• J Vet Emerg Crit Care (San Antonio) · Jul 2014

    Comparison of whole blood and plasma colloid osmotic pressure in healthy cats.

    • Mary L Jackson, Marie E Kerl, Beth Tynan, and F A Mann.
    • Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, 900 East Campus Drive, Columbia, MO, 65211.
    • J Vet Emerg Crit Care (San Antonio). 2014 Jul 1; 24 (4): 408-13.

    ObjectiveTo establish reference intervals for whole blood and plasma colloid osmotic pressure (COP) in healthy cats between the ages of 1 and 10 years using a cage-side colloid osmometer.DesignProspective, observational study.SettingsUniversity veterinary teaching hospital.AnimalsSixty-three healthy cats.InterventionsPhlebotomy.Measurements And Main ResultsWhole blood COP mean was 24.4 (±2.78) mmHg and plasma COP mean was 24.3 (±2.59) mmHg. Reference interval for our study population of feline whole blood COP was 18.9 to 30.4 mmHg, and for our study population of feline plasma COP was 18.3 to 30.8 mmHg. Difference of paired whole blood COP and plasma COP was +0.23 ± 1.68 mmHg (P = 0.32). There was no significant difference when comparing COP from neutered male and neutered female cats. Total protein and albumin were significantly correlated with whole blood COP (total protein to whole blood COP P < 0.0001, r = 0.53; albumin to whole blood COP P <0.0001, r = 0.68) and plasma COP (total protein to plasma COP P = 0.0025, r = 0.41; albumin to plasma COP P < 0.0001, r = 0.66).ConclusionsNo significant difference was found between mean whole blood and plasma COP in this study population of cats. Even though not statistically significant, evaluation of paired whole blood COP and plasma COP did reveal a slight difference; therefore, it seems prudent to maintain sample consistency for serial evaluations in cats.© Veterinary Emergency and Critical Care Society 2014.

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