• Ther Umsch · Nov 2012

    Review Comparative Study

    [Laboratory diagnostic with regard to new anticoagulants - monitoring and influence on coagulation tests].

    • M Nagler and W Wuillemin.
    • Universitätsklinik für Hämatologie und Hämatologisches Zentrallabor, Inselspital, Bern.
    • Ther Umsch. 2012 Nov 1; 69 (11): 650-6.

    AbstractNew oral anticoagulants promise to overcome essential drawbacks of traditional substances. They have a predictable therapeutic effect, a wide therapeutic window, only limited interaction with food and drugs and can be administered p.o. with a fixed dose. On the other hand, knowledge on the laboratory management of new anticoagulants is limited. In the present article we discuss possible indications and available assays for monitoring of Rivaroxaban, Apixaban and Dabigatran. Furthermore, we discuss interpretation of routine coagulation tests during therapy with these new drugs.

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