• Pflugers Arch. · Jul 2010

    Review

    Transient receptor potential channelopathies.

    • Bernd Nilius and Grzegorz Owsianik.
    • Laboratory Ion Channel Research, Department of Molecular Cell Biology, KU Leuven, Campus Gasthuisberg, Herestraat 49, bus 802, Leuven, Belgium. Bernd.Nilius@med.kuleuven.be
    • Pflugers Arch. 2010 Jul 1; 460 (2): 437-50.

    AbstractIn the past years, several hereditary diseases caused by defects in transient receptor potential channels (TRP) genes have been described. This review summarizes our current knowledge about TRP channelopathies and their possible pathomechanisms. Based on available genetic indications, we will also describe several putative pathological conditions in which (mal)function of TRP channels could be anticipated.

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