• J Pediatr Ophthalmol Strabismus · Mar 1992

    Case Reports

    A case of developmental glaucoma presenting with abdominal colic and subnormal intraocular pressure.

    • E M Talbot, J F Pitts, J Dudgeon, and W R Lee.
    • Royal Hospital for Sick Children, Yorkhill, Glasgow, Scotland, UK.
    • J Pediatr Ophthalmol Strabismus. 1992 Mar 1; 29 (2): 116-9.

    AbstractA healthy baby boy presented with abdominal colic. He was subsequently noted to have enlarged, edematous corneas. A clinical diagnosis of developmental glaucoma was made despite ocular hypotony. Trabeculectomies were designed to include peripheral cornea. This served as a biopsy to confirm the diagnosis and as a surgical treatment for the condition. Morphological examination of the outflow system revealed findings compatible with a diagnosis of developmental glaucoma: a hypoplastic trabecular meshwork which contained an abundance of abnormal collagenous tissue in the extracellular spaces and the presence of endothelial cells overlying a continuous collagenous membrane. In the iris stroma there were numerous abnormal blood vessels, with a paucity of mural contractile cells.

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