• Nature reviews. Neurology · Feb 2013

    Review

    Multiple sclerosis in 2012: Novel therapeutic options and drug targets in MS.

    • Axel Methner and Frauke Zipp.
    • Focus Program Translational Neuroscience, Rhine Main Neuroscience Network, Johannes Gutenberg University Medical Centre Mainz, Department of Neurology, Langenbeckstrasse 1, D-55131 Mainz, Germany. axel.methner@unimedizin-mainz.de
    • Nat Rev Neurol. 2013 Feb 1; 9 (2): 72-3.

    Abstract2012 witnessed important developments for multiple sclerosis, including successful phase III trials of novel oral therapeutics and identification of the potassium channel KIR4.1 as an autoimmune target. Additionally, the lung was highlighted as an important site for immune-cell programming, and the relevance of a TNF receptor variant was clarified.

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