• Z Aga, M Machina, and S A McCluskey.
• University of Toronto, Faculty of Medicine, Toronto, Ontario, Canada Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
• Br J Anaesth. 2016 Jun 1; 116 (6): 804-10.

BackgroundWe carried out a retrospective assessment of whether perioperative fluid volume was associated with length of hospital stay (LOS) after colorectal surgery.MethodsA single-centre chart review was conducted on colorectal surgeries that took place between January 2008 and December 2013. The primary outcome was LOS, with prolonged LOS defined as greater than median LOS. Secondary outcomes included postoperative pulmonary oedema, acute renal failure, myocardial infarction, and mortality. Univariate analysis, multivariable logistic regression, and quantile regression analyses were conducted to examine the association between perioperative fluid volume and prolonged LOS.ResultsOf the 1242 procedures, 57% were elective, 62% oncological, and 31% laparoscopic. The median LOS was 8.2 days (interquartile range 5.2, 14.7). Patients received 3.2 (sd 1.5) litres of fluid in the perioperative period (operating and recovery rooms), predominantly crystalloid. The volume (in litres) of perioperative fluid was independently associated with prolonged LOS (odds ratio 1.23, 95% confidence interval 1.10-1.36, P<0.01). This association persisted across the spectrum of definitions for prolonged LOS (10th-90th percentile). Logistic regression analysis also revealed that prolonged LOS was associated with age >65 yr, Charlson Co-morbidity Index ≥3, use of colloids, emergent surgery, estimated blood loss >200 ml, preoperative anaemia, erythrocyte transfusion, open surgeries, and surgical duration >4 h (C-statistic=0.79, Hosmer-Lemeshow=0.36).ConclusionsGreater perioperative fluid volume was independently associated with prolonged duration of recovery across a spectrum of surgical risk profiles. Fluid restriction should be considered a part of the care package in enhanced recovery after surgery programmes for colorectal surgery.© The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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