• Javier Valero, Domingo Desantes, Alfredo Perales-Puchalt, Juan Rubio, Vicente J Diago Almela, and Alfredo Perales.
• Obstetrics Department, University Hospital La Fe, Valencia, Spain.
• Eur. J. Obstet. Gynecol. Reprod. Biol. 2012 May 1; 162 (1): 21-3.

ObjectiveTo ascertain if there are differences in umbilical cord blood gas analysis between immediate and delayed cord clamping.Study DesignIn a prospective observational study on 60 vaginally delivered healthy term newborns, we sampled umbilical cord blood immediately after delivery and at the time umbilical cord pulsation spontaneously ceased.ResultsThere were significant decreases in pH, oxygen saturation (sO(2)), glycemia, oxygen content (ctO(2)), bicarbonate (HCO(3)(-)) and base excess (BE). Lactate and [Formula: see text] increased. Delayed cord clamping pH correlated with immediate cord clamping pH, [Formula: see text] , ctHb, sO(2) and time (r(2)=0.77, p<0.000). Delayed cord clamping lactate was associated with immediate cord clamping lactate and time (r(2)=0.83, p<0.000). Delayed BE was associated with previous pH, lactate, glycemia, ctHb and time (r(2)=0.83, p<0.000).ConclusionsDelayed cord clamping alters acid-base parameters and lactate values compared to immediate cord clamping. Those variations depend mainly on time, prior pH and lactate.Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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