• J Med Case Rep · Apr 2016

    Editorial

    How to apply case reports in clinical practice using surrogate models via example of the trigeminocardiac reflex.

    • Nora Sandu, Tumul Chowdhury, Bernhard J Schaller, and Trigemino-Cardiac Reflex Examination Group (TCREG).
    • Departement of Research, University of Southampton, University Road, Southampton, SO17 1BJ, UK.
    • J Med Case Rep. 2016 Apr 6; 10: 84.

    AbstractCase reports are an increasing source of evidence in clinical medicine. Until a few years ago, such case reports were emerged into systematic reviews and nowadays they are often fitted to the development of clinical (thinking) models. We describe this modern progress of knowledge creation by the example of the trigeminocardiac reflex that was first described in 1999 by a case series and was developed over the cause-and-effect relationship, triangulation to systematic reviews and finally to thinking models. Therefore, this editorial not only underlines the increasing and outstanding importance of (unique) case reports in current science, but also in current clinical decision-making and therefore also that of specific journals like the Journal of Medical Case Reports.

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