• Chest Surg. Clin. N. Am. · Feb 1994

    Randomized Controlled Trial Multicenter Study Clinical Trial

    Current status of screening for lung cancer.

    • B J Flehinger and M R Melamed.
    • Mathematical Sciences Department, T.J. Watson Research Center, Yorktown Heights, New York.
    • Chest Surg. Clin. N. Am. 1994 Feb 1; 4 (1): 1-15.

    AbstractThree parallel studies on screening for lung cancer, supported by the National Cancer Institute, were carried out by the Mayo Clinic, Johns Hopkins Medical Institutions, and Memorial Sloan-Kettering Center from 1971 to 1982. No significant mortality improvement was established that could be attributed to cytologic screening examinations. Many stage I lung cancers were detected by radiographic screening, with excellent changes for long-term survival. Patients with stage I cancers who were operated on had significantly better survival rates than those who failed to undergo surgery. Statistical modeling, however, indicates that long-term annual screening of a high-risk population would decrease lung cancer mortality by no more than 18%.

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