• Seminars in nephrology · Jan 2012

    Review

    Fluid overload assessment and management in heart failure patients.

    • Tertius Tuy and W Frank Peacock.
    • Duke-National University of Singapore Graduate Medical School, Singapore, Singapore.
    • Semin. Nephrol. 2012 Jan 1; 32 (1): 112-20.

    AbstractHeart failure is a syndrome in which myocardial function is incapable of providing for normal physiologic needs. In the acute care setting, cardiac dysfunction primarily manifests with volume perturbations and presents with signs and symptoms of vascular congestion. Thus, in acute heart failure volume assessment is crucial in diagnosing and improving the prognosis. Also, goal-directed therapy relies on accurate volume assessment to minimize the adverse outcomes of inappropriate, ineffective, or excessive diuresis. Currently, in most institutions clinical methods of volume assessment are the mainstay. However, these methods are highly dependent on the practitioners' skill level. In fact, there is a high variability between experienced physicians when assessing volume. As adjuncts, objective methods of volume assessment are being developed and used such as natriuretic peptides, bioimpedance analysis, and imaging.Copyright © 2012 Elsevier Inc. All rights reserved.

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