• Tidsskr. Nor. Laegeforen. · Sep 2005

    Review

    [Glucocorticoids reduce acute postoperative pain].

    • Luis Romundstad, Harald Breivik, and Audun Stubhaug.
    • Anestesiavdelingen, Rikshospitalet, 0027 Oslo. luisro@medisin.uio.no
    • Tidsskr. Nor. Laegeforen. 2005 Sep 22; 125 (18): 2507-8.

    AbstractGlucocorticoids have been used for postsurgical pain relief over the last 30 years. They reduce prostaglandins by inhibiting phospholipase A2 and the expression of COX-2 mRNA. The evidence for an analgesic effect is best after oral, orthopaedic, laparoscopic and perianal surgery. Their anti-emetic properties in addition to the analgesic effects make them particularly useful perioperatively.

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