• Transfusion · Oct 2002

    Comparative Study

    Racial and ethnic composition of volunteer cord blood donors: comparison with volunteer unrelated marrow donors.

    • Karen K Ballen, Julie Hicks, Bernie Dharan, Daniel Ambruso, Kenneth Anderson, Celso Bianco, Lynn Bemiller, William Dickey, Richard Lottenberg, Mary O'Neill, Mark Popovsky, Donna Skerrett, Irena Sniecinski, and John R Wingard.
    • American Red Cross Cord Blood Program, University of Massachusetts Memorial Health Care, Worcester, MA, USA. kballen@partners.org
    • Transfusion. 2002 Oct 1; 42 (10): 1279-84.

    BackgroundUmbilical cord blood is an alternative peripheral blood progenitor cell source for patients who need transplantation. A presumed advantage of cord blood is the ability to increase minority recruitment.Study Design And MethodsThe racial composition of five member cord blood banks of the National Marrow Donor Program (NMDP) was compared, representing 9020 cord blood donors with NMDP marrow donors from comparable geographic areas, representing 417,676 donors. Cord blood and marrow donors self-reported racial designations on questionnaires. Donor statistics were compared with baseline racial data of deliveries from participating hospitals for cord blood donors and with geographic census data for marrow donors.ResultsThe California, Florida, and Massachusetts cord blood banks recruited a lower percentage of minorities than the corresponding marrow donor centers. In New York and Colorado, minority recruitment was equivalent. In California, Florida, Massachusetts, and New York, the cord blood banks recruited a lower percentage of minorities than those delivering at the respective hospitals. The cord blood banks in California, Colorado, Florida, and Massachusetts recruited a lower percentage of minorities compared with delivery data than the corresponding marrow donor centers compared with census population (p < 0.001). In New York, the percentages were similar.ConclusionThe problem of insufficient minority recruitment of cord blood has not yet been solved. Better strategies are needed to recruit minority donors.

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