[Transition from intravenous to subcutaneous prostacyclin in

Rev Esp Cardiol · Aug 2003

[Transition from intravenous to subcutaneous prostacyclin in pulmonary hypertension].

Treatment of arterial pulmonary hypertension with epoprostenol (intravenous prostacyclin) improves survival and quality of life, but the need for an implanted central venous catheter is associated with frequent complications, that often (as in the case of infection or dislodgment) are serious and require catheter replacement. Treprostinil is a prostacyclin analogue suitable for continuous subcutaneous administration. We report the successful transition from intravenous epoprostenol to subcutaneuos treprostinil in four patients with severe pulmonary hypertension who suffered from serious complications associated with the epoprostenol infusion system.

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- Pilar Escribano Subías, Luis Cea-Calvo, Rocío Tello de Menesses, Miguel A Gómez Sánchez, Juan F Delgado Jiménez, and Carlos Sáenz de la Calzada.
- Servicio de Cardiología. Unidad de Hipertensión Pulmonar, Insuficiencia Cardíaca y Trasplante Cardíaco. Hospital Universitario 12 de Octubre. Madrid. España. med022585@saludalia.com
- Rev Esp Cardiol. 2003 Aug 1; 56 (8): 818-21.
AbstractTreatment of arterial pulmonary hypertension with epoprostenol (intravenous prostacyclin) improves survival and quality of life, but the need for an implanted central venous catheter is associated with frequent complications, that often (as in the case of infection or dislodgment) are serious and require catheter replacement. Treprostinil is a prostacyclin analogue suitable for continuous subcutaneous administration. We report the successful transition from intravenous epoprostenol to subcutaneuos treprostinil in four patients with severe pulmonary hypertension who suffered from serious complications associated with the epoprostenol infusion system.

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[Transition from intravenous to subcutaneous prostacyclin in pulmonary hypertension].

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