• Seizure · Apr 2011

    Case Reports

    Successful treatment of refractory simple motor status epilepticus with lacosamide and levetiracetam.

    • Leo L K Chen, Zulfi Haneef, Andrew Dorsch, Inna Keselman, and John M Stern.
    • David Geffen School of Medicine at UCLA, Neurology, Los Angeles, CA, United States; VA Greater Los Angeles Health Care System, Neurology, Los Angeles, CA 90095, United States. llchen@mednet.ucla.edu
    • Seizure. 2011 Apr 1; 20 (3): 263-5.

    AbstractLacosamide has been reported to have been successfully used for non-convulsive status epilepticus after benzodiazepine failure, and convulsive status epilepticus after benzodiazepine and levetiracetam failure. We report a case of simple motor status epilepticus refractory to benzodiazepines and multiple anti-epileptic medications (AEDs) over 4 days. The addition of lacosamide in combination with existing levetiracetam aborted the continuous seizure with maintenance of seizure freedom through the most recent follow-up at 4 weeks.Published by Elsevier Ltd.

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