[Dabigatran as cause of severe gastrointestinal bleeding in a

Ugeskrift for laeger · Feb 2013

Case Reports

[Dabigatran as cause of severe gastrointestinal bleeding in a Jehovah's Witness patient].

We report a case of severe gastrointestinal bleeding in a Jehovah's Witness patient after ten days of treatment with dabigatran. The patient refused to have a blood transfusion due to belief. ⋯ The patient was in a life-threatening condition and the haemoglobin level fell to nadir 2 mmol/l, before the bleeding stopped after one week's pause of dabigatran therapy. Since an antidote to dabigatran does not exist, precaution is needed when treating patients, who might refuse to have blood transfusion.

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- Jakob Holm and Mustafa Taskiran.
- Kardiologisk Afsnit, Medicinsk Afdeling, Køge Sygehus, Lykkebækvej 1, 4600 Køge, Denmark. jakobph@hotmail.com
- Ugeskr. Laeg. 2013 Feb 4; 175 (6): 334-6.
AbstractWe report a case of severe gastrointestinal bleeding in a Jehovah's Witness patient after ten days of treatment with dabigatran. The patient refused to have a blood transfusion due to belief. An endoscopic examination showed diffuse bleeding from her colonic mucosa, which is typical for medical induced bleedings. The patient was in a life-threatening condition and the haemoglobin level fell to nadir 2 mmol/l, before the bleeding stopped after one week's pause of dabigatran therapy. Since an antidote to dabigatran does not exist, precaution is needed when treating patients, who might refuse to have blood transfusion.

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[Dabigatran as cause of severe gastrointestinal bleeding in a Jehovah's Witness patient].

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