• Pediatric emergency care · Jun 2017

    Review Case Reports

    Acute Focal Bacterial Nephritis Associated With Central Nervous System Manifestations: A Report of 2 Cases and Review of the Literature.

    • Yuki Kasuga, Tatsuo Fuchigami, Ayumi Fukuda, Satoko Takahashi, Takemi Murai, Ryuuta Yonezawa, Michio Miyashita, Ryutaro Kohira, Yukihiko Fujita, and Shori Takahashi.
    • From the *Department of Pediatrics and Child Health, and †Division of Medical Education Planning and Development, Nihon University School of Medicine, Tokyo, Japan.
    • Pediatr Emerg Care. 2017 Jun 1; 33 (6): 418-421.

    AbstractAcute focal bacterial nephritis (AFBN) is a localized bacterial infection of the kidney presenting as an inflammatory mass without frank abscess formation. In children, most patients with AFBN present with nonspecific conditions, such as fever, vomiting, and abdominal pain. A small number of reported cases are accompanied by neurological symptoms, including meningeal irritation, unconsciousness, and seizures. We experienced 2 rare cases of AFBN associated with central nervous system lesions. The first case was a 3-year-old girl who had neurological symptoms, including unconsciousness and seizures, with AFBN associated with acute reversible encephalopathy. The second case was a 5-year-old girl who had neurological symptoms, including unconsciousness, with AFBN accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion.

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