• Maja Surbatović, Zoran Vesić, Dragan Djordjević, Sonja Radaković, Snjeiana Zeba, Dusko Jovanović, and Marijan Novaković.
• Klinika za anesteziologiju i intenzivnu terapiju, Vojnomedicinska akademija, Beograd, Srbija. maja.surbatovic@gmail.com
• Vojnosanit Pregl. 2012 Nov 1; 69 (11): 967-72.

Background/AimLaparoscopic cholecystectomy can be a greater challenge for anesthesiologist than for surgeon if the patient is ASA III with concomitant cardiovascular diseases. The aim of our study was to compare the effect of total intravenous anesthesia (TIVA--propofol with midazolam) and general balanced anesthesia (GBA--midazolam, thiopenton, nitrous oxide and 02) on hemodynamic stability in the ASA III patients who underwent laparoscopic cholecystectomy.MethodsIn our study, 60 patients were randomized into two groups depending on whether they received TIVA or GBA. Heart rate, systolic, diastolic and mean arterial pressure were monitored continuously and recorded in five time intervals.ResultsStatistical analysis showed that TIVA with propofol provides better hemodynamic stability (less than 10% deviation from basal values for each measured parameter) then GBA group (p < 0.01).ConclusionTotal intravenous anesthesia with propofol provides better hemodynamic stability for ASA III patients with concomitant cardiovascular diseases then GBA.

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