• Harefuah · May 1998

    Clinical Trial

    [Intravenous lignocaine for chronic pain: an 18-month experience].

    • A Cahana, V Shvelzon, O Dolberg, F Magora, and Y Shir.
    • Pain Treatment Services, Dept. of Anesthesiology of Sheba Medical Center, University Hospital, Jerusalem.
    • Harefuah. 1998 May 1; 134 (9): 692-4, 751, 750.

    AbstractIntravenous injection of lignocaine relieves pain in animals with experimentally induced pain, and in man, mainly those with neuropathic pain. 106 patients were treated with intravenous lignocaine during a period of 18 months (212 treatment sessions). Blood pressure, heart rate and pain scores were continuously monitored after an intravenous bolus of lignocaine, 1 mg/kg, followed by continuous infusion of lignocaine, 5 mg/kg during 1 hour. There was significant pain relief after each session in most patients, lasting from a few hours to 4 weeks. There were no significant side effects. We present 2 of our patients. Due to its simplicity, efficacy and safety, intravenous lignocaine injection is recommended for those with neuropathic pain unrelieved by other therapeutic modalities.

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